Polycystic ovary syndrome (PCOS) is a common hormonal disorder affecting women of reproductive age worldwide. It leads to irregular menstrual cycles, fertility issues, and lowers quality of life, while raising risks of serious health problems like heart disease and endometrial cancer.
Although its exact causes are unclear, both genetics and environment play a role.
As PCOS rates rise globally, drug treatments have become essential. Metformin, a medication that improves insulin sensitivity, has shown promise in managing PCOS.
Research indicates metformin can help with puberty-related issues, pregnancy complications, and long-term health in women with PCOS. However, questions remain about how well it works and the biological processes involved.
This review explores how metformin improves infertility linked to PCOS, highlighting its wide-ranging effects from puberty through pregnancy and beyond. These insights help guide better clinical use of metformin for women with PCOS.
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