Celebrities and social media influencers turning to weight-loss injections such as Ozempic and Wegovy are increasingly seeking labiaplasty and other intimate procedures after experiencing a side effect specialists are calling “Ozempic vagina.” The condition, caused by rapid fat loss, can result in sagging, loss of volume, and discomfort in the genital area.
Plastic surgeons say this trend represents an unexpected consequence of the popular diabetes drugs, now widely repurposed for weight management. Dr. Domenico Mileto, a plastic surgeon at mya.co.uk, confirmed that his clinic has seen a surge of women seeking reconstructive procedures to address changes caused by fast weight reduction.
Rapid Weight Loss Impacts Skin Elasticity
“Sudden weight loss, whether from lifestyle changes or weight-loss injections, can affect skin elasticity across the body — and the vaginal area is no exception,” Dr. Mileto explained. “A reduction in fat in the labia majora can leave the skin loose or sagging, causing irritation from clothing, discomfort during exercise, or even pain during sex.”
He added that many patients are motivated by comfort rather than purely aesthetic concerns. “Women often avoid tight clothing, certain workouts like spinning or running, and in some cases report hygiene issues or recurrent infections due to excess tissue,” he said.
‘Ozempic Vagina’ Gains Recognition in Hollywood
The phenomenon, colloquially termed “Ozempic vagina,” mirrors changes seen elsewhere in the body following rapid weight loss when skin fails to retract. Dr. Shirin Lakhani, founder of elite-aesthetics.co.uk, noted that sudden fat loss can make the vulva appear “deflated or saggy.”
“Weight-loss injections have made medical fat reduction widely accessible, but the aesthetic side effects do not discriminate by age,” Dr. Lakhani said.
Demand for Labiaplasty Spikes
Dr. Mo Akhavani, a consultant plastic surgeon at theplasticsurgerygroup.co.uk, reported a 75% increase in labiaplasty requests over the past two years, many from women using Ozempic or similar medications.
“Labiaplasty is one of our most requested procedures. For some patients, surgery alleviates pain and discomfort; for others, it restores confidence and a sense of how their body once felt,” he said.
Dr. Mileto emphasized that the procedure is largely reconstructive. “While labiaplasty is sometimes labeled purely cosmetic, most women seek it to regain comfort and improve function, not just appearance,” he said.
Minimally Invasive Options Available
For patients reluctant to undergo surgery, Dr. Lakhani highlighted less invasive treatments such as radiofrequency skin tightening and labial fillers. “These options can restore volume and improve laxity safely. It’s about confidence, comfort, and wellbeing, not vanity,” she said.
Hollywood Celebrities Acknowledge Use
Celebrities have openly discussed using GLP-1 medications like Ozempic and Mounjaro. Actor Tracy Morgan, 55, confirmed using Ozempic for appetite suppression. Singer Meghan Trainor shared her post-pregnancy weight-loss journey with Mounjaro on Instagram. Sharon Osbourne reported losing roughly 42 pounds with Ozempic, noting how it left her looking frail. Other high-profile users include Oprah Winfrey and Rebel Wilson, though Wilson no longer relies on the drug.
A senior source at a Beverly Hills cosmetic clinic told RadarOnline.com: “In the past six months, we’ve seen an unprecedented number of high-profile clients seeking procedures to correct what they describe as ‘sagging down there.’ They love their slimmer bodies but are surprised by these intimate side effects. Requests range from labial fillers to full reconstructive surgery — it’s the new quiet obsession in Hollywood.”
